Skip to main content

Chargers vs. 49ers DFS Advice: Optimal Lineups, Targets, Strategy (2022 Fantasy Football)

Chargers vs. 49ers DFS Advice: Optimal Lineups, Targets, Strategy (2022 Fantasy Football)

Daily Fantasy Contests require a different strategy than what you use to set your weekly lineups, and that’s even more true for these “island” or “standalone” games (Thursday Night Football, Sunday Night Football, Monday Night Football, etc.). In these contests, you typically have only a handful of lineup spots and players from just two teams to choose from. Just as importantly, everyone else playing in those contests is also choosing from those limited options. If you want to win money (or at least win “big” money in GPP contests), you have to be savvy and take some risks.

I’ll walk you through the current optimal lineups for FanDuel, DraftKings, Yahoo and OwnersBox via our DFS Lineup Optimizer and share some of my notes and strategies for this particular matchup. Note: these are the current optimal lineups, and I sometimes take some liberties based on recent news and my personal preferences and projections. For updated lineups based on adjusted projections throughout the day, be sure to access the DFS Lineup Optimizer tool and create your own lineups.

If you want to dive deeper into fantasy football, be sure to check out our award-winning slate of Fantasy Football Tools as you navigate your season. From our Start/Sit Assistant – which provides your optimal lineup, based on accurate consensus projections – to our Waiver Wire Assistant – that allows you to quickly see which available players will improve your team and by how much – we’ve got you covered this fantasy football season.

Feel free to reach out on Twitter @mikeMaher with questions or feedback anytime.

Optimal Lineups for Chargers vs. 49ers (Sunday Night Football, Week 10)

FanDuel Optimal Lineup (GPP)

Week 10
POS PLAYER PROJ. PTS SALARY
1.5x J. Herbert
LAC @ SF
37.3 $15,000
FLEX C. McCaffrey
LAC @ SF
26.6 $17,000
FLEX J. Garoppolo
LAC @ SF
21.8 $14,000
FLEX E. Mitchell
LAC @ SF
10.0 $6,000
FLEX D. Carter
LAC @ SF
9.3 $8,000
Totals 104.9 $60,000

 

Notes

We’re missing Austin Ekeler here, but we include both quarterbacks and Christian McCaffrey. The somewhat contrarian dart throw here is Elijah Mitchell, who is returning from injured reserve. He, of course, lost his starting job to McCaffrey, but he’s an interesting gamble here, considering the San Francisco offense and a Los Angeles defense that is more concerned with stopping the pass than the run. DeAndre Carter is an affordable lineup builder who should see plenty of opportunities due to the injuries to Mike Williams and Keenan Allen.

DraftKings Optimal Lineup (GPP)

Week 10
POS PLAYER PROJ. PTS SALARY
CPT C. McCaffrey
LAC @ SF
32.9 $17,400
FLEX A. Ekeler
LAC @ SF
21.6 $11,200
FLEX J. Herbert
LAC @ SF
17.9 $10,600
FLEX E. Mitchell
LAC @ SF
3.6 $200
FLEX J. Palmer
LAC @ SF
13.7 $7,800
FLEX M. Bandy
LAC @ SF
5.5 $2,400
Totals 95.2 $49,600

 

Notes

DraftKings makes you declare two players before it lets our lineup optimizer provide your best lineup. So, unlike FanDuel, this lineup won’t be universal because it depends on your initial choices.

This is a top-heavy lineup with McCaffrey, Ekeler, and Justin Herbert taking up a large chunk of our salary. Joshua Palmer is a lineup builder due to his salary and projected role with Allen and Williams out. Mitchell we walked about in the FanDuel section. At just $200, he’s essentially free on DraftKings. And Michael Bandy is another dart throw, but he saw eight targets last week and could see a similar workload on Sunday night.

Yahoo Optimal Lineup (GPP)

POS PLAYER PROJ. PTS SALARY
1.5x C. McCaffrey
LAC @ SF
39.8 $43
FLEX J. Herbert
LAC @ SF
24.9 $33
FLEX J. Garoppolo
LAC @ SF
21.8 $26
FLEX D. Samuel
LAC @ SF
18.0 $24
FLEX G. Everett
LAC @ SF
11.7 $14
Totals 116.3 $140

 

Notes

We have our first Deebo Samuel lineup. We’re McCaffrey in the MVP slot again and are utilizing both quarterbacks. Gerald Everett is affordable at $14 and has received 17 targets over his last two games and 24 over his last three games. Like others we’ve mentioned here, he could see an increased role with the Allen/Williams duo out.

OwnersBox Optimal Lineup (GPP)

POS PLAYER PROJ. PTS SALARY
QB J. Garoppolo
LAC @ SF
21.8 $6,200
RB C. McCaffrey
LAC @ SF
29.9 $6,700
RB A. Ekeler
LAC @ SF
28.2 $6,800
WR B. Aiyuk
LAC @ SF
17.8 $5,700
WR M. Bandy
LAC @ SF
8.1 $3,900
TE G. Everett
LAC @ SF
13.4 $4,600
FLEX G. Kittle
LAC @ SF
17.7 $5,000
FLEX E. Mitchell
LAC @ SF
10.7 $4,000
SF J. Herbert
LAC @ SF
24.9 $6,900
Totals 172.4 $49,800

 

Notes

Unlike the other platforms, OwnersBox still uses full lineups for island games. So, this lineup will be different from the others, and you are almost forced to use a couple of dart throws in order to affordably build your lineup. OwnersBox also defines the positions and includes a superflex slot, as opposed to the MVP/Flex setup.

We’ve covered most of the names here already. Brandon Aiyuk is one of the new faces here. He’s only $5,700 and has finished as a WR1 in two of the last three weeks. We’re also flexing George Kittle since OwnersBox only has him at $5,000.

Lineup Builders / Core

Christian McCaffrey (RB – SF)

Joshua Palmer (WR – LAC)

Justin Herbert (QB – LAC)

Austin Ekeler (RB – LAC)

Gerald Everett (TE – LAC)

DeAndre Carter (WR – LAC)

Dart Throws

Elijah Mitchell (RB – SF)

Michael Bandy (WR – LAC)

Feel free to reach out on Twitter @mikeMaher with questions or feedback anytime.

Subscribe: Apple Podcasts | Spotify | Google Podcasts | Stitcher | SoundCloud | iHeartRadio

If you want to dive deeper into fantasy football, check out our award-winning slate of Fantasy Football Tools as you navigate your season. From our Start/Sit Assistant – which provides your optimal lineup based on accurate consensus projections – to our Waiver Wire Assistant, which allows you to quickly see which available players will improve your team and how much – we’ve got you covered this fantasy football season.

More Articles

FantasyPros Dynasty Football Podcast: How Much is Your First-Round Draft Pick Worth?

FantasyPros Dynasty Football Podcast: How Much is Your First-Round Draft Pick Worth?

fp-headshot by FantasyPros Staff | 2 min read
3 Dynasty Fantasy Football Trade Targets: Running Backs (2024)

3 Dynasty Fantasy Football Trade Targets: Running Backs (2024)

fp-headshot by Anthony Corrente | 2 min read
Fantasy Football Mock Draft: FFPC Best Ball Picks (2024)

Fantasy Football Mock Draft: FFPC Best Ball Picks (2024)

fp-headshot by Tom Strachan | 3 min read
3 Fantasy Football Draft Picks to Avoid: Tight Ends (2024)

3 Fantasy Football Draft Picks to Avoid: Tight Ends (2024)

fp-headshot by Mike Fanelli | 2 min read

About Author

Hide

Current Article

3 min read

FantasyPros Dynasty Football Podcast: How Much is Your First-Round Draft Pick Worth?

Next Up - FantasyPros Dynasty Football Podcast: How Much is Your First-Round Draft Pick Worth?

Next Article