| Player | Team | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | TTL | AVG |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ronald Jones II | TB | 9% | 41% | 16% | 17% | 14% | 19% | 19% | 15% | bye | 0% | 19% | 18% | 3% | 10% | 30% | 52% | 27% | 0% | 218 | 20% |
| Leonard Fournette | TB | 65% | 49% | 36% | 82% | 62% | 63% | 53% | 61% | bye | 65% | 59% | 81% | 87% | 80% | 45% | 0% | 0% | 0% | 623 | 63% |
| Giovani Bernard | TB | 26% | 10% | 45% | 0% | 23% | 16% | 15% | 21% | bye | 29% | 10% | 0% | 10% | 0% | 0% | 0% | 0% | 0% | 138 | 20% |
| Tony Pollard | DAL | 24% | 34% | 38% | 30% | 40% | 29% | bye | 26% | 39% | 42% | 33% | 42% | 40% | 0% | 41% | 34% | 30% | 0% | 374 | 34% |
| Ezekiel Elliott | DAL | 83% | 71% | 70% | 75% | 60% | 71% | bye | 75% | 53% | 49% | 69% | 64% | 64% | 64% | 62% | 58% | 70% | 60% | 809 | 66% |
| Corey Clement | DAL | 1% | 0% | 4% | 0% | 0% | 0% | bye | 0% | 8% | 17% | 0% | 0% | 0% | 36% | 0% | 10% | 0% | 27% | 77 | 15% |
| Mekhi Sargent | Multi | 2% | 0% | 1% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 3% | 0% | 0% | 0% | 0% | 3% | 6 | 2% |
| Derrick Henry | TEN | 63% | 76% | 72% | 59% | 77% | 81% | 74% | 74% | 0% | 0% | 0% | 0% | bye | 0% | 0% | 0% | 0% | 0% | 411 | 71% |
| Jeremy McNichols | TEN | 36% | 24% | 26% | 40% | 23% | 0% | 15% | 23% | 45% | 27% | 0% | 0% | bye | 38% | 29% | 42% | 10% | 0% | 268 | 29% |
| Khari Blasingame | TEN | 14% | 0% | 0% | 0% | 0% | 17% | 0% | 0% | 0% | 0% | 0% | 8% | bye | 0% | 0% | 15% | 0% | 21% | 46 | 15% |