Top 3 Fantasy Football Storylines of Week 10 (2025)

The NFL is a week-to-week league, filled with changes. One pass-catching corps might be forced into changes due to an injury. Another team is coming out of the bye, and it will be interesting to see if they make meaningful changes after a week of self-scouting. Finally, would an NFC team that received a jolt of life from a quarterback change really go back to their diminutive starter?

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Fantasy Football Storylines

How Will New England’s Passing Game Hierarchy Shake Out This Week?

Unfortunately, Kayshon Boutte suffered a grade 1 hamstring strain in Week 9.

#Patriots WR Kayshon Boutte announced on his Discord server that an MRI revealed he has a grade 1 hamstring strain.

Boutte adds that there is a chance he could play Sunday against Tampa Bay. pic.twitter.com/bYosKY7nLZ

— Carlos A. Lopez (@LosTalksPats) November 3, 2025

According to the Fantasy Points data suite, Boutte ran only 12 routes before exiting with an injury. Stefon Diggs, Hunter Henry and TreVeyon Henderson paced the Patriots in routes (27), followed by Mack Hollins (20), Kyle Williams (19), Austin Hooper (16), DeMario Douglas (13) and Jack Westover (13).

Drake Maye spread the ball around, with seven players catching a pass and five catching multiple passes. However, no one dominated the work, with Henry, Douglas and Henderson tying for the team lead in receptions in Week 9 (four).

Interestingly, despite Douglas’ lackluster 32.5% route participation rate, he had a 45.8% air yards share, 21.8-yard average depth of target (aDOT), 20.7% target share, 0.46 targets per route run, a team-high 31.6% first-read rate, 100 receiving yards and a touchdown.

Douglas won’t necessarily see a surge in route participation if Boutte is out. However, New England’s diminutive slot wideout could play more often if they use more 3-WR sets against a pass-funnel defense. According to RotoViz’s pace app, the Buccaneers have faced a 61% situation-neutral pass rate this year. Still, Douglas is a volatile fantasy option, even if Boutte’s hamstring sidelines him this week.

Diggs should be viewed as New England’s primary passing-game weapon in the event Boutte is out. He had a ho-hum 20.3% air yards share, 13.8% target share, three receptions, 38 receiving yards and a touchdown last week.

Nevertheless, the veteran wideout is second on the club in air yards share (21.7%), first in target share (20.6%), tied for first in targets per route run (0.25), first in receptions (45), first in receiving yards per game (56.4), first in yards per route run (2.44 YPRR) and tied for third in receiving touchdowns (two) this season.

Henry is a low-end TE1 to high-end TE2. Yet, he could see a slight uptick in usage this week if Boutte isn’t healthy enough to play.

What will the Jets Look Post-Bye?

The Jets were rumored to have plans to bench Justin Fields for Tyrod Taylor in Week 8. Owner Woody Johnson even ragged on Gang Green’s passing game during that week. However, Taylor was limited the entire week with a knee injury and ruled out, leaving Fields to start and earn the club’s first win of the season in a comeback against the Bengals.

According to Pro-Football-Reference, Fields didn’t take any sacks for the first time in a game this year in Week 8, passed for the second-most yards (244) he had in a game this season and had his second-most adjusted net yards per pass attempt (8.25) against Cincinnati’s inept defense. Presumably, Fields will get another opportunity to start.

Fields will have a much more challenging matchup against the Browns this week. Since the team was already seemingly considering benching him, Fields is presumably at risk of an in-game benching if Myles Garrett and company bring the worst out of the sack-prone signal-caller.

It’s unclear who the Jets will have available among skill-position players, too. Breece Hall could be traded before the NFL’s trade deadline, and Garrett Wilson is working through a knee injury. Gamers will know if Hall is still a Jet by tonight. If the team trades him, Isaiah Davis would be a viable Flex or desperation RB2, even in a brutal fantasy matchup for running backs.

Head coach Aaron Glenn already declared Wilson would practice this week. How the club’s No. 1 wide receiver responds to practicing and his level of participation will go a long way toward determining his availability against the Browns. Fields’ inconsistency as a passer creates a low floor for Wilson. At the same time, the potential for Glenn to yank Fields if he struggles mightily and turn to Taylor provides some hope that the quarterbacking can be only so bad, and Wilson is a target hog.

Among 78 wide receivers with at least 150 routes this year, Wilson is third in air yards share (43.9%), third in target share (31.2%), tied for 12th in targets per route run (0.26) and 11th in expected half-PPR points per game (16.0) this season. Wilson is a no-brainer fantasy starter in leagues of all sizes, even with the quarterbacking inconsistency, as soon as he suits up again.

Will the Cardinals Go Back to Kyler Murray?

The Cardinals were 2-3 in Kyler Murray’s starts before he was injured, and Jacoby Brissett has gone 1-2 in Murray’s stead. However, there’s no question the offense has played better with Brissett. The team scored 20, 27, 15, 20 and 21 points in Week 1 through Week 5 with Murray. They’ve scored 27, 23 and 27 points in Brissett’s three starts.

Brissett has averaged 286.7 passing yards per game with precisely two passing touchdowns in all three of his starts, and he added a rushing score against the Cowboys on Monday Night Football in Week 9. The Cardinals have a challenging matchup on a quick turnaround against the Seahawks in Seattle on Sunday.

Murray produced only 200 passing yards at 4.9 yards per attempt against the Seahawks on Thursday Night Football in Week 4. According to SumerSports, the Seahawks are tied for seventh in expected points added (EPA) allowed per play this year, which would make for a tricky matchup for Murray to return to.

Gamers shouldn’t bench Trey McBride under any circumstances. Still, his value would take a hit if the Cards re-inserted Murray as the team’s starter. Marvin Harrison Jr. would take an even more substantial hit to his fantasy value.

Harrison barbecued Dallas’ pitiful secondary for seven receptions, 96 receiving yards and a touchdown. He was knocked out of Brissett’s first start early with a concussion. In Brissett’s first two starts this year, Harrison put up the following stats:

• 25.2% air yards share
• 0.18 targets per route run
• 4 receptions
• 45 receiving yards
• 1.76 yards per route run

The Seahawks are a poor matchup for wideouts. Nevertheless, Harrison would be a viable WR3 or Flex option if Brissett starts.

Josh Shepardson is a featured writer at FantasyPros. For more from Josh, check out his archive and follow him @BChad50.