| Player | Team | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | TTL | AVG |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Matthew Stafford | LAR | 67 | 62 | 48 | 74 | 65 | 65 | bye | 58 | 57 | 0 | 38 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 534 | 59.3 |
| Josh Allen | BUF | 59 | 52 | 92 | 64 | 48 | 73 | bye | 59 | 62 | 75 | 65 | 77 | 75 | 59 | 78 | 64 | 0 | 59 | 1061 | 66.3 |
| Marcus Mariota | ATL | 75 | 61 | 57 | 55 | 66 | 58 | 47 | 67 | 61 | 63 | 55 | 57 | 54 | bye | 0 | 0 | 0 | 0 | 776 | 59.7 |
| Jameis Winston | NO | 61 | 66 | 69 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | bye | 0 | 0 | 0 | 0 | 196 | 65.3 |
| Joe Flacco | NYJ | 84 | 70 | 78 | 0 | 0 | 0 | 0 | 0 | 0 | bye | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 56 | 295 | 59.0 |
| Lamar Jackson | BAL | 56 | 59 | 60 | 70 | 65 | 59 | 64 | 76 | 68 | bye | 69 | 72 | 10 | 0 | 0 | 0 | 0 | 0 | 728 | 60.7 |
| Joe Burrow | CIN | 100 | 70 | 68 | 64 | 63 | 57 | 68 | 53 | 58 | bye | 66 | 70 | 72 | 67 | 66 | 83 | 0 | 66 | 1091 | 68.2 |
| Mitchell Trubisky | PIT | 63 | 59 | 59 | 33 | 0 | 27 | 0 | 0 | bye | 0 | 0 | 0 | 0 | 47 | 68 | 0 | 0 | 0 | 356 | 50.9 |
| Tua Tagovailoa | MIA | 60 | 71 | 40 | 25 | 0 | 0 | 62 | 68 | 57 | 62 | bye | 55 | 45 | 51 | 59 | 50 | 0 | 0 | 705 | 54.2 |
| Mac Jones | NE | 57 | 68 | 66 | 0 | 0 | 0 | 18 | 78 | 63 | bye | 63 | 55 | 54 | 59 | 65 | 56 | 60 | 68 | 830 | 59.3 |