The Colts face the 49ers in San Francisco after the host’s bye week last week. The game’s over/under suggests a low-scoring affair. However, the small spread hints at a close game if things go according to the betting odds.
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Game: Indianapolis Colts at San Francisco 49ers
Spread: SF -4.0 Points
Over/Under: 43.0 Points
Colts Analysis: Don't look now, but the Colts' offense is rounding into form. They've scored 25 points or more with 349 yards of offense or more in three straight, per Pro-Football-Reference. Unfortunately, it looks like they'll be without T.Y. Hilton after his rock-solid season debut last week.