As we get to the end of June, we have hit a lull in NFL news. There’s the odd contract extension here or there, but largely it’s wait-and-see time until training camp. This, of course, means it’s an excellent time to start seriously thinking about your drafts.
What better way to prepare for your fantasy football draft than by completing FREE mocks with our fantasy football mock draft simulator?
This series will give you an overview of what you can expect to see no matter which first-round pick you draw. In what feels like a very strong first round in 2025, nailing your picks will be more important than ever.
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Fantasy Football Draft Strategy: Pick 1.10
Let’s dive into our approach for the fantasy football 1.10 pick for upcoming drafts.
We look into the players likely to be available, highlight players to target/avoid and share a mock draft from the 1.10 draft slot to help you prepare for your fantasy football draft.
Players to Consider at 1.10 Fantasy Football Draft Pick
Here are players likely available when you make your selection:
Players to Target at 1.10 Fantasy Football Draft Pick
As the summer goes on, don’t be surprised if average draft position (ADP) pushes running backs higher up draftboards, particularly if Christian McCaffrey stays healthy, but for now, both McCaffrey and Ashton Jeanty should be available to consider in this range.
It would be naive to put Christian McCaffrey this high without acknowledging this pick won’t be for everyone. Risk tolerance plays a big part in whether you’ll be drafting McCaffrey in 2025, given he’s only played over 11 games once in the last four years.
When he is on the field, though, he’s typically a league-winning type of back who brings elite volume and elite pass-catching skills.
According to reports, McCaffrey took part in everything at organized team activities (OTAs), including some drills most veterans sat out, indicating he’s over the Achilles issues he suffered through in 2024.
If he can stay healthy, he can potentially be a league winner once again. In 2023, when McCaffrey was last healthy, he ranked first in rushing yards (1,459), second in yards per carry (5.36), fourth in explosive run rate (7.4%) and first in missed tackles forced (63).
With no Deebo Samuel and Brandon Aiyuk recovering from a multi-ligament knee injury, the stage is set for McCaffrey to prove he can be an elite RB once again.
Whenever we draft rookie running backs this high, it’s worth remembering that since 1984, the only rookie to finish as the RB1 was Saquon Barkley in 2018.
However, it’s also worth considering that Ashton Jeanty belongs right in the same tier of prospect as Barkley was when he entered the league.
Jeanty possesses rare qualities in his vision and pass-catching abilities, and with Geno Smith at quarterback, he’ll play with someone comfortable getting the ball to his best players.
Jeanty averaged over six yards per carry in each of his last two seasons and didn’t catch a ton of passes in his final season because he was routinely taking the ball to the house.
The Raiders had no problem drafting Jeanty with the sixth overall pick, and it’s hard not to want to do so in fantasy drafts when he could be a lock for 300+ touches in his rookie season.
One of the true bright spots of 2024 fantasy football was Malik Nabers, who broke Puka Nacua’s record for rookie receptions with 109. If it weren’t for Brock Bowers getting to 112, he might be talked up even further.
The argument against drafting Nabers last year was his poor quarterback situation, and while it isn’t exactly perfect this year, Nabers showed enough to assuage any doubts. Current reports suggest it’s a true battle between Russell Wilson and Jaxson Dart for the QB1 job, with Jameis Winston a distant third choice.
Any of those options could be better than last year’s quadrant of poor options. Among quarterbacks with 50+ dropbacks, Daniel Jones, Drew Lock, Tommy DeVito and Tim Boyle all ranked in the bottom 20% of yards per attempt (YPA), and only DeVito ranked above 40th in quarterback rating (33rd).
Wilson ranked 16th in quarterback rating and 18th in YPA, while the Giants believed in Dart enough to spend a first-round pick on him.
Nabers continues to have minimal competition around him, with Wan’Dale Robinson the most noteworthy. Nabers should be set for another top-10 positional finish, having finished as the fantasy WR6 in 2024.
One of the more divisive picks of the first round is Amon-Ra St. Brown, who some people view as potentially in trouble due to the emergence of Jameson Williams, as well as a healthy offseason for Sam LaPorta.
However, St. Brown has seen 140+ targets in each of the last three seasons, as well as seeing his touchdowns increase each year in the league to a career-high 12 in 2024.
In full PPR formats, St. Brown will be an easier click than in half-PPR leagues. Ultimately, how much should you worry about a receiver who has finished as the WR3 in total points for the last two seasons?
Since the start of the 2023 season, Nico Collins leads all wide receivers in yards per route run versus man coverage and his journey from zero to hero has been truly impressive. Whether Collins can crack the top receivers altogether is a tough question, but he’s an interesting upside swing at this point in the draft.
Collins is the obvious alpha in an offense featuring two new rookie receivers, the often-injured Christian Kirk and Tank Dell, who potentially could miss the entire season. According to Fantasy Points Data, Collis is the only wide receiver who has ranked inside the top 10 of yards per route run versus zone coverage and man coverage in back-to-back years.
In Weeks 1-5 last year, Collins was the WR2 overall, averaging 21.6 points per game before missing time with a hamstring injury. The injury history might be enough to put some people off, but one thing we’ve learned in fantasy football is that you’re injury prone until you’re not, and that presents an opportunity.
A true league-winner in 2024, available in the mid-rounds and coming up big down the stretch, Brian Thomas Jr. heads into his sophomore season with a new head coach in Liam Coen, who was one of the most desired offensive minds this offseason.
If Coen can help elevate Trevor Lawrence to the range people believed he was capable of coming out of college, we could see an even greater second season from Thomas, which is quite something to say when he finished third in receiving yardage behind only Justin Jefferson and Ja’Marr Chase.
Thomas was one of eight receivers to hit double-digit touchdowns last season. He achieved this despite being held to a 76% route participation up until Week 11; that number should be 90+ throughout 2025.
Players to Avoid at 1.10 Fantasy Football Draft Pick
It was a strange 2024 season for A.J. Brown. He recorded the second-highest target share among wide receivers (31.1%) and the fifth-most receiving yards per game (83). However, he finished as just the fantasy WR16 in total PPR points. Even on a per-game basis, this only jumped to WR13.
Brown’s 7.5 targets per game ranked 23rd among receivers, which highlights the uphill battle he faced while Saquon Barkley had a season for the history books.
Perhaps if Barkley regresses this year, or if the Eagles trend differently under new offensive coordinator Kevin Patullo, Brown can move back into the top tier of receivers. For now, the pick 1.10 is too costly for a player with question marks.
Let’s be clear, Ladd McConkey had an excellent rookie season, culminating in a dominant performance in the playoffs with 9/197/1 against the Texans. However, there are reasons to be skeptical that he could live up to his current ADP, which is edging towards round one.
Last year, the Chargers’ run game wasn’t effective, despite J.K. Dobbins‘ best efforts, and the Chargers elected to clean house and move on from both Dobbins and Gus Edwards, while seemingly sending Sione Vaki to the shadow realm. Najee Harris was signed in free agency and Omarion Hampton was added in the draft.
Both represent significant upgrades and should allow long-time ground-game lover, Greg Roman, to play to his strengths more. If that generates a more efficient offense, the need for passing could drop slightly. That is always a concern for receivers, like McConkey, who depend on volume. McConkey is an OK pick in the second round, but drafting him here would be a mistake.
Fantasy Football Mock Draft From the 1.10 Pick
We used our FREE fantasy football mock draft simulator to show you an example of a draft from the 1.10 position. You can sync your league for free and mock draft against your fantasy football league settings to prepare more specifically for your draft.
Here’s how our fantasy football mock draft from the 1.10 position turned out.
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