Fantasy Football Injury Updates & Predictions for Week 5 (2025)

Welcome back! Y’all know the drill.

As always, hit us up on Twitter/X @SportMDAnalysis or IG @sportsmedanalytics for more content throughout the week.

Now let’s get to it:

Week 5 Fantasy Football Injury Updates

*Injury glossary key:

  • FP = Full Participant
  • LP = Limited Participant
  • DNP = Did Not Practice

Brock Bowers (TE – LV)

Coach says playing. Data favors sitting. Practice reports suggests PCL setback. Data strongly suggests major dip if active

CeeDee Lamb (WR – DAL)

Suspect return Wk 6-7. Data favors Wk 7 as most likely. 20% re-injury risk

Bucky Irving (RB – TB)

Data strongly favors missing Wk 5+6. RBs avg 3 wks to regain workload

Lamar Jackson (QB – BAL)

Avg = 2 wks out. Suspect Wk 8 return (Wk 7 = bye)

George Kittle (TE – SF)

Lean Wk 6-7 return (Wk 7 = most likely). Rapid ramp up, 1-2 wks for targets

Brock Purdy (QB – SF)

Turf toe re-aggravation. Avg = 3 wks. Lean toward return ~Wk 8. HIGH risk if rushed

Jayden Daniels (QB – WAS)

No dip projected. Has led league in contact. Suspect emphasis on sliding

Chuba Hubbard (RB – CAR)

Avg = 2 wks. Likely out Wk 5+6

Mike Evans (WR – TB)

Possible return Wk 6, but data suggests Wk 7 = more likely. Rapid ramp up + HIGH re-injury risk (20-25%) given age + history

Chris Godwin (WR – TB)

Expect high usage. Data suggests volatile production next 5 wks + strong end to season

Trey Benson (RB – ARI)

IR. Avg = 5 wks. RBs see rapid ramp up, ~2 games to regain workload + efficiency

Miles Sanders (RB – DAL)

Wk 5 TBD. Data heavily favors sitting. Dip in touches if active

Michael Pittman Jr. (WR – IND)

Thurs hamstring = likely very minor. No dip

Alec Pierce (WR – IND)

Concussion setback. Data favors Wk 6 return w/o dip

Terry McLaurin (WR – WAS)

Avg = 3 wks out. Lean Wk 6-7 return. Moderate re-injury risk, ~15%

Deebo Samuel (WR – WAS)

Playing. Mild dip projected (DNP x2 -> FP this wk due to heel listing)

Tyjae Spears (TB – TEN)

Data projects 60% to play. RBs avg 4 game ramp up in touches

Bhayshul Tuten (RB – JAX) + Dyami Brown (WR – JAX)

Wk 5 TBD. Data leans toward playing. Mild dip projected

Will Dissly (TE – LAC)

Data strongly favors playing. Minimal dip in usage (~10%) projected

Michael Mayer (TE – LV)

Wk 5 TBD. Concussion protocol. Has chance to clear Sat. Data slightly favors playing. No dip if active

J.J. McCarthy (QB – MIN)

Suspect return Wk 7

Tyrone Tracy Jr. (RB – NYG)

Avg = 3 wks. Likely out Wk 5. May return Wk 6 but data projects dip if active

Ricky Pearsall (WR – SF)

Mild PCL sprain. Data favors playing Wk 6 but w/3-4 wk production hit

Jauan Jennings (WR – SF)

Limited info. Reports optimistic about Wk 6 return

Calvin Ridley (WR – TEN)

Wk 5 TBD. Data slightly favors sitting. Major dip projected if active

Joe Mixon (RB – HOU)

Suspect out for season

Joe Alt (OT – LAC)

High ankle. Avg 3 wks out. Likely return ~Wk 7

Mekhi Becton (OT – LAC)

Concussion. Chance to clear Sat

Tyler Booker (OL – DAL), Tyler Guyton (OT – DAL) + Tyler Smith (OL – DAL)

The Cowboys’ offensive line will be missing three players this week.

Matt Milano (LB – BUF) + Ed Oliver (DT – BUF)
Data favors playing for both

Marlon Humphrey (CB – BAL), Roquan Smith (LB – BAL) + Kyle Hamilton (S – BAL)

All three Ravens defensive stars are likely out

Kyle Van Noy (LB – BAL)

Playing. 15% Re-injury risk

That’s a wrap for now. Catch us Sunday night on the FantasyPros YouTube channel with the crew, breaking down the injuries and recapping the games right as they finish up.