NFL DFS Cheat Sheet: Picks for Every Game (Week 2)

There are a dozen games on the Week 2 NFL DFS main slate because there’s a Monday Night Football doubleheader. Below, I’ve highlighted my entire player pool for the Week 2 NFL DFS main slate. I will update the player pool to reflect who I’m using in the remaining three primetime games on Friday night. If any injury news prompts me to adjust the cheat sheet, I’ll update it this week with a timestamp and italicize the changes.

Updated on September 13, 2025, at 4:30 p.m. ET. Anyone added to the main slate suggestions since this was initially published on September 12, 2025, is in italics, and the showdown selections are now available.

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NFL DFS Cheat Sheet: Week 2

Sunday Main Slate

CIN vs. JAC

• Core Plays: Ja’Marr Chase, Joe Burrow, Tee Higgins, Brian Thomas, Travis Etienne, Brenton Strange
• GPP Only: Trevor Lawrence, Travis Hunter

NYJ vs. BUF

• Core Plays: Josh Allen
• GPP Only: Garrett Wilson, Breece Hall, Justin Fields, James Cook, Khalil Shakir, Keon Coleman, Josh Palmer, Dalton Kincaid

BAL vs. CLE

• Core Plays: Derrick Henry, Cedric Tillman, Harold Fannin
• GPP Only: Lamar Jackson, Zay Flowers

DAL vs. NYG

• Core Plays: None
• GPP Only: None

DET vs. CHI

• Core Plays: None
• GPP Only: None

MIA vs. NE

• Core Plays: Drake Maye, Kayshon Boutte
• GPP Only: NE DST

NO vs. SF

• Core Plays: Christian McCaffrey, Ricky Pearsall
• GPP Only: Mac Jones, SF DST

PIT vs. SEA

• Core Plays: PIT DST
• GPP Only: None

TEN vs. LAR

• Core Plays: None
• GPP Only: Calvin Ridley, Elic Ayomanor, Puka Nacua

ARI vs. CAR

• Core Plays: James Conner, ARI DST (FanDuel), Tetairoa McMillan
• GPP Only: ARI DST (DraftKings)

IND vs. DEN

• Core Plays: Tyler Warren, IND DST
• GPP Only: None

KC vs. PHI

• Core Plays: None
• GPP Only: None

Sunday Main Slate Core Plays

QB

• Joe Burrow
• Josh Allen
• Drake Maye

RB

• Travis Etienne
• Derrick Henry
• Christian McCaffrey
• James Conner

WR

• Ja’Marr Chase
• Tee Higgins
• Brian Thomas
• Cedric Tillman
• Kayshon Boutte
• Ricky Pearsall
• Tetairoa McMillan

TE

• Brenton Strange
• Harold Fannin
• Tyler Warren

DST

• PIT DST
• ARI DST (FanDuel)
• IND DST

Sunday Night Football

MIN vs. ATL

• Top shelf captains: Justin Jefferson, Bijan Robinson, Drake London
• Contrarian / Secondary captains: J.J. McCarthy. Michael Penix
• Flex only: Aaron Jones, Jordan Mason, Will Reichard, Adam Thielen, Jalen Nailor, Josh Oliver, Darnell Mooney, Kyle Pitts, Ray-Ray McCloud, Tyler Allgeier, Charlie Woerner

Monday Night Football

HOU vs. TB

• Top shelf captains: Nico Collins, Bucky Irving
• Contrarian / Secondary captains: C.J. Stroud, Nick Chubb, Mike Evans, Baker Mayfield, Emeka Egbuka
• Flex only: Jayden Higgins, Ka’imi Fairbairn, Dalton Schultz, HOU DST, Xavier Hutchinson, Justin Watson, Chase McLaughlin, TB DST, Sterling Shepard

Monday Night Football

LV vs. LAC

• Top shelf captains: Ashton Jeanty, Geno Smith, Ladd McConkey, Justin Herbert
• Contrarian / Secondary captains: Jakobi Meyers, Omarion Hampton, Quentin Johnston, Keenan Allen
• Flex only: Brock Bowers, Daniel Carlson, Tre Tucker, Dont’e Thornton, Michael Mayer, Cameron Dicker, Tyler Conklin, Will Dissly, KeAndre Lambert-Smith

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Josh Shepardson is a featured writer at FantasyPros. For more from Josh, check out his archive and follow him @BChad50.