NFL DFS Cheat Sheet: Picks for Every Game (Week 2)

There are a dozen games on the Week 2 NFL DFS main slate because there’s a Monday Night Football doubleheader. Below, I’ve highlighted my entire player pool for the Week 2 NFL DFS main slate. I will update the player pool to reflect who I’m using in the remaining three primetime games on Friday night. If any injury news prompts me to adjust the cheat sheet, I’ll update it this week with a timestamp and italicize the changes.

Updated on September 13, 2025, at 4:30 p.m. ET. Anyone added to the main slate suggestions since this was initially published on September 12, 2025, is in italics, and the showdown selections are now available.

NFL DFS Cheat Sheet: Week 2

Sunday Main Slate

CIN vs. JAC

NYJ vs. BUF

BAL vs. CLE

DAL vs. NYG

  • Core Plays: None
  • GPP Only: None

DET vs. CHI

  • Core Plays: None
  • GPP Only: None

MIA vs. NE

NO vs. SF

PIT vs. SEA

  • Core Plays: PIT DST
  • GPP Only: None

TEN vs. LAR

ARI vs. CAR

IND vs. DEN

KC vs. PHI

  • Core Plays: None
  • GPP Only: None

Sunday Main Slate Core Plays

QB

RB

WR

TE

DST

  • PIT DST
  • ARI DST (FanDuel)
  • IND DST

Sunday Night Football

MIN vs. ATL

Monday Night Football

HOU vs. TB

Monday Night Football

LV vs. LAC

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    Josh Shepardson is a featured writer at FantasyPros. For more from Josh, check out his archive and follow him @BChad50.