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Kansas City Chiefs RB Isiah Pacheco, who is dealing with a shoulder injury, has been ruled out of Sunday's Week 14 contest with the Buffalo Bills. (Source: Adam Schefter on Twitter)

Fantasy Impact: Pacheco did not practice all week as a result of his shoulder ailment, and thus he will not play on Sunday. In his place, the Chiefs will likely turn to RB Jerick McKinnon (who was limited Wednesday but full on Thursday) and Clyde Edwards-Helaire. It's also possible they call up a practice squad RB for depth like La'Mical Perine, Deneric Prince or the recently added Keaontay Ingram.

Joshua Dobbs will start for the Vikings in Week 14. (Source: Dianna Russini on Twitter)

Fantasy Impact: After Dobbs threw four picks in a dismal 12-10 loss to the Bears back in Week 12, the Vikings' coaching staff made it known that they would spend the bye week evaluating the QB position. With the team now getting set for a trip to Las Vegas, head coach Kevin O'Connell announced Wednesday that he would stick with Dobbs under center. Dobbs has played four games for the Vikings so far, completing 66.4 percent of his passes for an average of 208 yards with a 5-to-5 TD/INT ratio. He has added 142 and three touchdowns on 25 carries.

Zach Wilson named the starter for Week 14. (Source: Ian Rapoport on Twitter)

Fantasy Impact: Well, this is the conclusion of what has certainly been an interesting few days regarding the Jets' quarterback situation. Wilson will step back into the huddle after riding the bench the last two weeks. The third-year quarterback has played 10 games so far this season, completing 59.2 percent of his passes for an average of 194.4 yards with a 6-to-7 TD/INT ratio.

Marquise Brown (heel) is officially active for Week 13's game against the Pittsburgh Steelers. (Source: Darren Urban on Twitter)

Fantasy Impact: Brown will be able to play in Week 13, despite being originally listed as questionable to play. He's dealing with a heel injury of some kind that left him sidelined at practice all week, but the team needs him and doesn't seem to be concerned that he will suffer an aggravation to his injury. He hasn't been very reliable since the return of QB Kyler Murray but retains high upside on a week-to-week basis.

Keenan Allen (quad) is officially active for Week 13's game against the New England Patriots. (Source: Field Yates on Twitter)

Fantasy Impact: Allen was officially considered questionable to play heading into the weekend thanks to a quad injury that left him sidelined for most of the team's practices this week, but it's not a serious issue and he will be available to play through it on Sunday. He's one of the best players in fantasy and remains a must-start option in a favorable matchup against the Patriots.

Joe Flacco will start for the Browns in their Week 13 game against the Rams. (Source: Mary Kay Cabot)

Fantasy Impact: Dorian Thompson-Robinson was ruled out with a concussion, so the 38-year-old Flacco will take the reins. He started five games for the Jets last season and has 42,320 career passing yards. The Rams rank 14th against the pass, but it is hard to predict what fantasy production Flacco will provide in Week 13. With the bye weeks, he is a streamable QB in Superflex leagues, but use caution in other formats.

Aaron Rodgers (Achilles) can begin practicing with the Jets again after 21-day window opened Wednesday. (Source: Adam Schefter on Twitter)

Fantasy Impact: There had been reports a couple of weeks back that Rodgers may begin practicing with the Jets again in early December. Those have now come to fruition, as the team opened the veteran QB's practice window Wednesday by designating him to return from IR. Rodgers was originally expected to miss the entire season after tearing his Achilles back in Week 1.

The Panthers have fired first-year HC Frank Reich after a 1-10 start to the season, according to multiple reports. Special teams coordinator Chris Tabor will serve as interim HC. (Source: Tom Pelissero on Twitter)

Fantasy Impact: The Panthers hired Reich this offseason and assembled a QB-friendly offensive staff before trading up in the NFL Draft to select Alabama QB Bryce Young. Young and the Carolina offense have struggled to a 1-10 record through their first 11 games, while fellow first-year QB C.J. Stroud, who was selected No. 2 in the draft by the Houston Texans, is thriving to the point he is the favorite for Rookie of the Year and is in the MVP conversation. And the cherry on top is that, despite having the worst record in the NFL, the Panthers won't be able to use their first-round pick in 2024 to improve their roster because they traded that pick to the Bears as part of their 2023 NFL Draft move for Young. As for fantasy impact, things can't get much worse for the offensive playmakers in Carolina, and they may get a small short-term boost as a result of this move.

Dolphins RB De'Von Achane is officially inactive for a Week 12 matchup with the Jets.

Fantasy Impact: Achane is dealing with another knee injury and was limited in practice this week. Fantasy managers should expect Raheem Mostert to see the bulk of the touches with Jeff Wilson seeing snaps as the backup against a tough Jets’ defense.

Derek Carr (concussion) is no longer listed on the Saints' injury report. (Source: Matthew Paras on Twitter)

Fantasy Impact: Carr practiced in full on Wednesday and has cleared the NFL's concussion protocol. He was not included on the Saints' most recent injury, clearing the way for him to start Sunday in Atlanta. Carr has completed 65.9 percent of his passes for an average of 223.1 yards and just four interceptions through 10 games this season. However, his 10 touchdown passes and 10.1 yards per completion leave much to be desired to this point.

Bengals QB Joe Burrow will miss the remainder of the season with a torn ligament in his wrist. (Source: Ian Rapoport on Twitter )

Fantasy Impact: Bengals’ head coach Zac Taylor shared Friday that Burrow will require surgery for the torn ligament and the injury likely occurred on the play before he exited the game Thursday. Fantasy managers should downgrade the Bengals’ pass catchers moving forward, as Burrow’s absence will impact the efficiency of the offense moving forward. Jake Browning is expected to serve as the Bengals’ starting quarterback moving forward.

Ravens HC John Harbaugh told reporters after Thursday night's win over the Bengals that TE Mark Andrews is likely to miss the rest of the season with the ankle injury he suffered during the game. (Source: Adam Schefter on Twitter)

Fantasy Impact: Entering Week 11's matchup against the Bengals, Andrews had caught 43 of his 69 targets for 521 yards and six touchdowns and was TE3 on the season in Half PPR formats. Isaiah Likely will be the popular name to pick up with Andrews out, though he was unable to haul in either of his targets on Thursday. But Likely has flashed his receiving potential in the past and will have a clear path to opportunities on a good offense, which immediately makes him relevant at a thin position for fantasy managers.

Tee Higgins (hamstring) will be out for Thursday's game against the Ravens. (Source: Adam Schefter on Twitter)

Fantasy Impact: Higgins' status for this week has been in jeopardy from the start, so this is not necessarily an unexpected development. The fourth-year receiver will now miss his second straight game and third of the season. Tyler Boyd and Trenton Irwin will likely see an increase in targets once again.

Justin Fields (thumb) is back at Bears' practice Wednesday and expected to start in Week 11. (Source: Courtney Cronin on Twitter)

Fantasy Impact: Fields last played for the Bears exactly one month ago, but he has now been medically cleared for full activity and will start this Sunday at Detroit. Prior to injuring his thumb in Week 6, Fields had completed 61.8 percent of his passes for an average of 228.6 yards per game with an 11-to-6 TD/INT ratio. Fields has also rushed for 237 yards and a touchdown on 47 carries this season.

Deshaun Watson will undergo season-ending surgery on a broken bone in his throwing shoulder, the Cleveland Browns announced Wednesday morning. (Source: Cleveland Browns on X)

Fantasy Impact: Watson had an MRI on Monday on two separate injuries suffered during Sunday's game against the Baltimore Ravens. Imaging on his left ankle revealed a high-ankle sprain, and imaging on his right shoulder revealed a fracture. He'll have surgery to repair the shoulder injury and be placed on season-ending injured reserve. The Browns are 6-3 and firmly in the playoff hunt, and their backup quarterbacks are P.J. Walker and Dorian Thompson-Robinson. Thompson-Robinson played earlier this season after flashing his potential during the preseason, but he threw three interceptions against the Ravens in Week 4. Walker has played more recently when Watson has missed time, but he too has just one touchdown pass against five interceptions through parts of five games. The Browns traded QB Josh Dobbs to the Cardinals before the start of the season, and Dobbs has subsequently been traded to the Vikings, where he is playing well. The NFL trade deadline has already passed, so the Browns will have to rely on either Walker or Thompson-Robinson or look to free agency or the waiver wire for a replacement. Carson Wentz recently signed with the Los Angeles Rams.

Jaguars WR Zay Jones was arrested on a misdemeanor domestic battery charge Monday, ESPN's Michael DiRocco reports. He was booked on a charge of domestic battery causing bodily harm, a first-degree misdemeanor, and has a 9 am ET court appearance scheduled for Tuesday. (Source: ESPN)

Fantasy Impact: Jones has appeared in three games for the Jaguars this season as he has dealt with a knee injury, catching eight of his 18 targets for 78 yards and two touchdowns. Regardless of the outcome of his legal matter, Jones could face discipline from the Jaguars directly or from the NFL via its personal conduct policy. The Jacksonville offense relies primarily on RB Travis Etienne, TE Evan Engram and WRs Calvin Ridley and Christian Kirk. Jones is the No. 3 WR when healthy, but no obvious replacement has stepped up in his absence. After the aforementioned four starters, no Jaguars skill position player has even 100 receiving yards on the season.

T.J. Hockenson is officially active for Minnesota's Week 10 game against New Orleans.

Fantasy Impact: Hockenson is suiting up despite a rib injury that has limited him during the week. He has a tough matchup against the Saints, but he is still a must-start in fantasy.

Ja'Marr Chase (back) is officially active for Week 10 against the Houston Texans. (Source: Adam Schefter on Twitter)

Fantasy Impact: Chase has been dealing with back soreness all week and was questionable heading into the day Sunday, but he will be able to play through it and is officially active for Week 10. It remains to be seen if he will be limited in any way, but either way, he remains a must-start fantasy option against the Texans. The team will need to rely on Chase more than usual with Tee Higgins (hamstring) unavailable to play on Sunday.

Saints WR Michael Thomas was seen being escorted from his home by the Kenner Police Department after an altercation with another individual, according to local witnesses who spoke to WDSU News in New Orleans. Thomas is rumored to have thrown two bricks at the individual's truck before pushing him and slapping a phone out of his hand. A Saints spokesman told team reporters, “We are aware of the incident and are gathering information.” (Source: WDSU News)

Fantasy Impact: There is a lot of unknown here, so it's difficult to speculate on any potential fantasy impact. Even if Thomas was indeed arrested, we don't know if that will impact his availability for Week 10. The team acknowledging the incident lends it credence, however. Thomas is currently WR39 in Week 10 ECR, and he's coming off a game in which he failed to catch a pass on one target. Through nine games, he has caught 38 of his 62 targets for 439 yards and one touchdown. If Thomas is held out for Week 10, it could mean more targets for Chris Olave and Rashid Shaheed and more playing time for A.T. Perry and Lynn Bowden Jr.

Cardinals coach Jonathan Gannon confirmed Friday that Kyler Murray will start on Sunday against the Falcons. (Source: Darren Urban on Twitter)

Fantasy Impact: Murray will make his much anticipated season debut. There is some risk starting him in fantasy football, but the Cardinals played it safe with him to where he should be fully healthy.