Jeff Wilson Jr. could be in line to see the most carries in the 49ers backfield. With Raheem Mostert and Tevin Coleman out, the 49ers backfield will be left with Wilson Jr. and Jerick McKinnon. (San Francisco Chronicle)
Wilson Jr. has played well in the past when there have been injuries to the 49ers backfield. Although Wilson Jr. will be splitting time with McKinnon, he should see a good amount of carries and most of the goal-line work. Wilson Jr. comes with risk this week, but has RB2 upside in a good matchup against the New York Giants.