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Week 1 NFL DFS Cash Game Lineup Advice & Strategy (2022)

Week 1 NFL DFS Cash Game Lineup Advice & Strategy (2022)

The 2022 NFL regular season is finally upon us, and if we’re really being honest with one another, nobody has any clue what’s going to happen with this 13-game main slate on Sunday.

I mean, the experts told you to play Cam Akers (three carries and zero targets) while Darrell Henderson got 13 carries and five targets. Akers was on the field for just 12 snaps while Henderson played 55. Even Zack Moss, who was supposed to be buried behind Devin Singletary and James Cook, got six carries and six targets for the Bills.

It’s educated guesswork at this point. What we do know is there are two games with current Vegas totals over 50 points — mouth-watering matchups between the Chiefs and Cardinals and the Raiders and Chargers. Additionally, there are three more games with current totals of 46 or higher, so the opportunity for some fantasy fireworks surely exists in Week 1!


If you are looking for a data scientist to present hard-to-understand charts with little waves and fancy colors, you have come to the wrong spot. Most of this comes from my gut and watching and studying lots of football. The players below are the ones I’m considering for cash games on both the DraftKings and FanDuel main slates:

 

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