| Week 1 | Dallas Cowboys vs. Philadelphia Eagles | Thursday, September 4th, 2025 at 8:20pm ET |
| Week 2 | New York Giants vs. Dallas Cowboys | Sunday, September 14th, 2025 at 1:00pm ET |
| Week 3 | Dallas Cowboys vs. Chicago Bears | Sunday, September 21st, 2025 at 4:25pm ET |
| Week 4 | Green Bay Packers vs. Dallas Cowboys | Sunday, September 28th, 2025 at 8:20pm ET |
| Week 5 | Dallas Cowboys vs. New York Jets | Sunday, October 5th, 2025 at 1:00pm ET |
| Week 6 | Dallas Cowboys vs. Carolina Panthers | Sunday, October 12th, 2025 at 1:00pm ET |
| Week 7 | Washington Commanders vs. Dallas Cowboys | Sunday, October 19th, 2025 at 4:25pm ET |
| Week 8 | Dallas Cowboys vs. Denver Broncos | Sunday, October 26th, 2025 at 4:25pm ET |
| Week 9 | Arizona Cardinals vs. Dallas Cowboys | Monday, November 3rd, 2025 at 8:15pm ET |
| Week 10 | Bye Week | |
| Week 11 | Dallas Cowboys vs. Las Vegas Raiders | Monday, November 17th, 2025 at 8:15pm ET |
| Week 12 | Philadelphia Eagles vs. Dallas Cowboys | Sunday, November 23rd, 2025 at 4:25pm ET |
| Week 13 | Kansas City Chiefs vs. Dallas Cowboys | Thursday, November 27th, 2025 at 4:30pm ET |
| Week 14 | Dallas Cowboys vs. Detroit Lions | Thursday, December 4th, 2025 at 8:15pm ET |
| Week 15 | Minnesota Vikings vs. Dallas Cowboys | Sunday, December 14th, 2025 at 8:20pm ET |
| Week 16 | Los Angeles Chargers vs. Dallas Cowboys | Sunday, December 21st, 2025 at 1:00pm ET |
| Week 17 | Dallas Cowboys vs. Washington Commanders | Thursday, December 25th, 2025 at 1:00pm ET |
| Week 18 | Dallas Cowboys vs. New York Giants | Sunday, January 4th, 2026 at 1:00pm ET |
