| Week 1 | Miami Dolphins vs. Los Angeles Chargers | Sunday, September 10th, 2023 at 4:25pm ET |
| Week 2 | Los Angeles Chargers vs. Tennessee Titans | Sunday, September 17th, 2023 at 1:00pm ET |
| Week 3 | Los Angeles Chargers vs. Minnesota Vikings | Sunday, September 24th, 2023 at 1:00pm ET |
| Week 4 | Las Vegas Raiders vs. Los Angeles Chargers | Sunday, October 1st, 2023 at 4:05pm ET |
| Week 5 | Bye Week | |
| Week 6 | Dallas Cowboys vs. Los Angeles Chargers | Monday, October 16th, 2023 at 8:15pm ET |
| Week 7 | Los Angeles Chargers vs. Kansas City Chiefs | Sunday, October 22nd, 2023 at 4:25pm ET |
| Week 8 | Chicago Bears vs. Los Angeles Chargers | Sunday, October 29th, 2023 at 8:20pm ET |
| Week 9 | Los Angeles Chargers vs. New York Jets | Monday, November 6th, 2023 at 8:15pm ET |
| Week 10 | Detroit Lions vs. Los Angeles Chargers | Sunday, November 12th, 2023 at 4:05pm ET |
| Week 11 | Los Angeles Chargers vs. Green Bay Packers | Sunday, November 19th, 2023 at 1:00pm ET |
| Week 12 | Baltimore Ravens vs. Los Angeles Chargers | Sunday, November 26th, 2023 at 8:20pm ET |
| Week 13 | Los Angeles Chargers vs. New England Patriots | Sunday, December 3rd, 2023 at 1:00pm ET |
| Week 14 | Denver Broncos vs. Los Angeles Chargers | Sunday, December 10th, 2023 at 4:25pm ET |
| Week 15 | Los Angeles Chargers vs. Las Vegas Raiders | Thursday, December 14th, 2023 at 8:15pm ET |
| Week 16 | Buffalo Bills vs. Los Angeles Chargers | Saturday, December 23rd, 2023 at 8:00pm ET |
| Week 17 | Los Angeles Chargers vs. Denver Broncos | Sunday, December 31st, 2023 at 4:25pm ET |
| Week 18 | Kansas City Chiefs vs. Los Angeles Chargers | Sunday, January 7th, 2024 at 4:25pm ET |
