| Week 1 | Las Vegas Raiders vs. Los Angeles Chargers | Sunday, September 8th, 2024 at 4:05pm ET |
| Week 2 | Los Angeles Chargers vs. Carolina Panthers | Sunday, September 15th, 2024 at 1:00pm ET |
| Week 3 | Los Angeles Chargers vs. Pittsburgh Steelers | Sunday, September 22nd, 2024 at 1:00pm ET |
| Week 4 | Kansas City Chiefs vs. Los Angeles Chargers | Sunday, September 29th, 2024 at 4:25pm ET |
| Week 5 | Bye Week | |
| Week 6 | Los Angeles Chargers vs. Denver Broncos | Sunday, October 13th, 2024 at 4:05pm ET |
| Week 7 | Los Angeles Chargers vs. Arizona Cardinals | Monday, October 21st, 2024 at 9:00pm ET |
| Week 8 | New Orleans Saints vs. Los Angeles Chargers | Sunday, October 27th, 2024 at 4:05pm ET |
| Week 9 | Los Angeles Chargers vs. Cleveland Browns | Sunday, November 3rd, 2024 at 1:00pm ET |
| Week 10 | Tennessee Titans vs. Los Angeles Chargers | Sunday, November 10th, 2024 at 4:05pm ET |
| Week 11 | Cincinnati Bengals vs. Los Angeles Chargers | Sunday, November 17th, 2024 at 8:20pm ET |
| Week 12 | Baltimore Ravens vs. Los Angeles Chargers | Monday, November 25th, 2024 at 8:15pm ET |
| Week 13 | Los Angeles Chargers vs. Atlanta Falcons | Sunday, December 1st, 2024 at 1:00pm ET |
| Week 14 | Los Angeles Chargers vs. Kansas City Chiefs | Sunday, December 8th, 2024 at 8:20pm ET |
| Week 15 | Tampa Bay Buccaneers vs. Los Angeles Chargers | Sunday, December 15th, 2024 at 4:25pm ET |
| Week 16 | Denver Broncos vs. Los Angeles Chargers | Thursday, December 19th, 2024 at 8:15pm ET |
| Week 17 | Los Angeles Chargers vs. New England Patriots | Saturday, December 28th, 2024 at 1:00pm ET |
| Week 18 | Los Angeles Chargers vs. Las Vegas Raiders | Sunday, January 5th, 2025 at 4:25pm ET |
