| Week 1 | Miami Dolphins vs. Indianapolis Colts | Sunday, September 7th, 2025 at 1:00pm ET |
| Week 2 | New England Patriots vs. Miami Dolphins | Sunday, September 14th, 2025 at 1:00pm ET |
| Week 3 | Miami Dolphins vs. Buffalo Bills | Thursday, September 18th, 2025 at 8:15pm ET |
| Week 4 | New York Jets vs. Miami Dolphins | Monday, September 29th, 2025 at 7:15pm ET |
| Week 5 | Miami Dolphins vs. Carolina Panthers | Sunday, October 5th, 2025 at 1:00pm ET |
| Week 6 | Los Angeles Chargers vs. Miami Dolphins | Sunday, October 12th, 2025 at 1:00pm ET |
| Week 7 | Miami Dolphins vs. Cleveland Browns | Sunday, October 19th, 2025 at 1:00pm ET |
| Week 8 | Miami Dolphins vs. Atlanta Falcons | Sunday, October 26th, 2025 at 1:00pm ET |
| Week 9 | Baltimore Ravens vs. Miami Dolphins | Thursday, October 30th, 2025 at 8:15pm ET |
| Week 10 | Buffalo Bills vs. Miami Dolphins | Sunday, November 9th, 2025 at 1:00pm ET |
| Week 11 | Washington Commanders vs. Miami Dolphins | Sunday, November 16th, 2025 at 9:30am ET |
| Week 12 | Bye Week | |
| Week 13 | New Orleans Saints vs. Miami Dolphins | Sunday, November 30th, 2025 at 1:00pm ET |
| Week 14 | Miami Dolphins vs. New York Jets | Sunday, December 7th, 2025 at 1:00pm ET |
| Week 15 | Miami Dolphins vs. Pittsburgh Steelers | Monday, December 15th, 2025 at 8:15pm ET |
| Week 16 | Cincinnati Bengals vs. Miami Dolphins | Sunday, December 21st, 2025 at 1:00pm ET |
| Week 17 | Tampa Bay Buccaneers vs. Miami Dolphins | Sunday, December 28th, 2025 at 1:00pm ET |
| Week 18 | Miami Dolphins vs. New England Patriots | Sunday, January 4th, 2026 at 1:00pm ET |
