| Week 1 | New England Patriots vs. Miami Dolphins | Sunday, September 11th, 2022 at 1:00pm ET |
| Week 2 | Miami Dolphins vs. Baltimore Ravens | Sunday, September 18th, 2022 at 1:00pm ET |
| Week 3 | Buffalo Bills vs. Miami Dolphins | Sunday, September 25th, 2022 at 1:00pm ET |
| Week 4 | Miami Dolphins vs. Cincinnati Bengals | Thursday, September 29th, 2022 at 8:15pm ET |
| Week 5 | Miami Dolphins vs. New York Jets | Sunday, October 9th, 2022 at 1:00pm ET |
| Week 6 | Minnesota Vikings vs. Miami Dolphins | Sunday, October 16th, 2022 at 1:00pm ET |
| Week 7 | Pittsburgh Steelers vs. Miami Dolphins | Sunday, October 23rd, 2022 at 8:20pm ET |
| Week 8 | Miami Dolphins vs. Detroit Lions | Sunday, October 30th, 2022 at 1:00pm ET |
| Week 9 | Miami Dolphins vs. Chicago Bears | Sunday, November 6th, 2022 at 1:00pm ET |
| Week 10 | Cleveland Browns vs. Miami Dolphins | Sunday, November 13th, 2022 at 1:00pm ET |
| Week 11 | Bye Week | |
| Week 12 | Houston Texans vs. Miami Dolphins | Sunday, November 27th, 2022 at 1:00pm ET |
| Week 13 | Miami Dolphins vs. San Francisco 49ers | Sunday, December 4th, 2022 at 4:05pm ET |
| Week 14 | Miami Dolphins vs. Los Angeles Chargers | Sunday, December 11th, 2022 at 4:05pm ET |
| Week 15 | Miami Dolphins vs. Buffalo Bills | Sunday, December 18th, 2022 at 1:00pm ET |
| Week 16 | Green Bay Packers vs. Miami Dolphins | Sunday, December 25th, 2022 at 1:00pm ET |
| Week 17 | Miami Dolphins vs. New England Patriots | Sunday, January 1st, 2023 at 1:00pm ET |
| Week 18 | New York Jets vs. Miami Dolphins | Sunday, January 8th, 2023 at 1:00pm ET |
