| Week 1 | Cincinnati Bengals vs. Cleveland Browns | Sunday, September 7th, 2025 at 1:00pm ET |
| Week 2 | Jacksonville Jaguars vs. Cincinnati Bengals | Sunday, September 14th, 2025 at 1:00pm ET |
| Week 3 | Cincinnati Bengals vs. Minnesota Vikings | Sunday, September 21st, 2025 at 1:00pm ET |
| Week 4 | Cincinnati Bengals vs. Denver Broncos | Monday, September 29th, 2025 at 8:15pm ET |
| Week 5 | Detroit Lions vs. Cincinnati Bengals | Sunday, October 5th, 2025 at 4:25pm ET |
| Week 6 | Cincinnati Bengals vs. Green Bay Packers | Sunday, October 12th, 2025 at 4:25pm ET |
| Week 7 | Pittsburgh Steelers vs. Cincinnati Bengals | Thursday, October 16th, 2025 at 8:15pm ET |
| Week 8 | New York Jets vs. Cincinnati Bengals | Sunday, October 26th, 2025 at 1:00pm ET |
| Week 9 | Chicago Bears vs. Cincinnati Bengals | Sunday, November 2nd, 2025 at 1:00pm ET |
| Week 10 | Bye Week | |
| Week 11 | Cincinnati Bengals vs. Pittsburgh Steelers | Sunday, November 16th, 2025 at 1:00pm ET |
| Week 12 | New England Patriots vs. Cincinnati Bengals | Sunday, November 23rd, 2025 at 1:00pm ET |
| Week 13 | Cincinnati Bengals vs. Baltimore Ravens | Thursday, November 27th, 2025 at 8:20pm ET |
| Week 14 | Cincinnati Bengals vs. Buffalo Bills | Sunday, December 7th, 2025 at 1:00pm ET |
| Week 15 | Baltimore Ravens vs. Cincinnati Bengals | Sunday, December 14th, 2025 at 1:00pm ET |
| Week 16 | Cincinnati Bengals vs. Miami Dolphins | Sunday, December 21st, 2025 at 8:20pm ET |
| Week 17 | Arizona Cardinals vs. Cincinnati Bengals | Sunday, December 28th, 2025 at 1:00pm ET |
| Week 18 | Cleveland Browns vs. Cincinnati Bengals | Sunday, January 4th, 2026 at 1:00pm ET |
