| Week 1 | Detroit Lions vs. Green Bay Packers | Sunday, September 7th, 2025 at 4:25pm ET |
| Week 2 | Washington Commanders vs. Green Bay Packers | Thursday, September 11th, 2025 at 8:15pm ET |
| Week 3 | Green Bay Packers vs. Cleveland Browns | Sunday, September 21st, 2025 at 1:00pm ET |
| Week 4 | Green Bay Packers vs. Dallas Cowboys | Sunday, September 28th, 2025 at 8:20pm ET |
| Week 5 | Bye Week | |
| Week 6 | Cincinnati Bengals vs. Green Bay Packers | Sunday, October 12th, 2025 at 4:25pm ET |
| Week 7 | Green Bay Packers vs. Arizona Cardinals | Sunday, October 19th, 2025 at 4:25pm ET |
| Week 8 | Green Bay Packers vs. Pittsburgh Steelers | Sunday, October 26th, 2025 at 8:20pm ET |
| Week 9 | Carolina Panthers vs. Green Bay Packers | Sunday, November 2nd, 2025 at 1:00pm ET |
| Week 10 | Philadelphia Eagles vs. Green Bay Packers | Monday, November 10th, 2025 at 8:15pm ET |
| Week 11 | Green Bay Packers vs. New York Giants | Sunday, November 16th, 2025 at 1:00pm ET |
| Week 12 | Minnesota Vikings vs. Green Bay Packers | Sunday, November 23rd, 2025 at 1:00pm ET |
| Week 13 | Green Bay Packers vs. Detroit Lions | Thursday, November 27th, 2025 at 1:00pm ET |
| Week 14 | Chicago Bears vs. Green Bay Packers | Sunday, December 7th, 2025 at 1:00pm ET |
| Week 15 | Green Bay Packers vs. Denver Broncos | Sunday, December 14th, 2025 at 4:25pm ET |
| Week 16 | Green Bay Packers vs. Chicago Bears | Saturday, December 20th, 2025 at 1:00pm ET |
| Week 17 | Baltimore Ravens vs. Green Bay Packers | Sunday, December 28th, 2025 at 1:00pm ET |
| Week 18 | Green Bay Packers vs. Minnesota Vikings | Sunday, January 4th, 2026 at 1:00pm ET |
