| Week 1 | Jacksonville Jaguars vs. Indianapolis Colts | Sunday, September 10th, 2023 at 1:00pm ET |
| Week 2 | Kansas City Chiefs vs. Jacksonville Jaguars | Sunday, September 17th, 2023 at 1:00pm ET |
| Week 3 | Houston Texans vs. Jacksonville Jaguars | Sunday, September 24th, 2023 at 1:00pm ET |
| Week 4 | Atlanta Falcons vs. Jacksonville Jaguars | Sunday, October 1st, 2023 at 9:30am ET |
| Week 5 | Jacksonville Jaguars vs. Buffalo Bills | Sunday, October 8th, 2023 at 9:30am ET |
| Week 6 | Indianapolis Colts vs. Jacksonville Jaguars | Sunday, October 15th, 2023 at 1:00pm ET |
| Week 7 | Jacksonville Jaguars vs. New Orleans Saints | Thursday, October 19th, 2023 at 8:15pm ET |
| Week 8 | Jacksonville Jaguars vs. Pittsburgh Steelers | Sunday, October 29th, 2023 at 1:00pm ET |
| Week 9 | Bye Week | |
| Week 10 | San Francisco 49ers vs. Jacksonville Jaguars | Sunday, November 12th, 2023 at 1:00pm ET |
| Week 11 | Tennessee Titans vs. Jacksonville Jaguars | Sunday, November 19th, 2023 at 1:00pm ET |
| Week 12 | Jacksonville Jaguars vs. Houston Texans | Sunday, November 26th, 2023 at 1:00pm ET |
| Week 13 | Cincinnati Bengals vs. Jacksonville Jaguars | Monday, December 4th, 2023 at 8:15pm ET |
| Week 14 | Jacksonville Jaguars vs. Cleveland Browns | Sunday, December 10th, 2023 at 1:00pm ET |
| Week 15 | Baltimore Ravens vs. Jacksonville Jaguars | Sunday, December 17th, 2023 at 8:20pm ET |
| Week 16 | Jacksonville Jaguars vs. Tampa Bay Buccaneers | Sunday, December 24th, 2023 at 4:05pm ET |
| Week 17 | Carolina Panthers vs. Jacksonville Jaguars | Sunday, December 31st, 2023 at 1:00pm ET |
| Week 18 | Jacksonville Jaguars vs. Tennessee Titans | Sunday, January 7th, 2024 at 1:00pm ET |
