Elijah Mitchell is expected to miss some time with the knee injury that led to him leaving Week 1 early. The San Francisco running back underwent an MRI to determine the severity of the injury on Monday. (Ian Rapoport on Twitter)
Although the MRI will determine exactly how long Mitchell will be out, he is already looking at a multi-week absence. After he left on Sunday, Jeff Wilson and Jordan Mason split carries out of the backfield, so they are both worth a waiver pickup. However, expect Deebo Samuel to eat into their workload out of the backfield in his role as the team's "wide back," boosting his fantasy upside.